Sustainable Catalysis: Challenges and Practices for the Pharmaceutical and Fine Chemical Industries Peter J Dunn

ISBN: 9781118354513

Published: April 1st 2013

ebook

440 pages


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Sustainable Catalysis: Challenges and Practices for the Pharmaceutical and Fine Chemical Industries  by  Peter J Dunn

Sustainable Catalysis: Challenges and Practices for the Pharmaceutical and Fine Chemical Industries by Peter J Dunn
April 1st 2013 | ebook | PDF, EPUB, FB2, DjVu, audiobook, mp3, RTF | 440 pages | ISBN: 9781118354513 | 10.28 Mb

Opens the door to the sustainable production of pharmaceuticals and fine chemicalsDriven by both public demand and government regulations, pharmaceutical and fine chemical manufacturers are increasingly seeking to replace stoichiometric reagents usedMoreOpens the door to the sustainable production of pharmaceuticals and fine chemicalsDriven by both public demand and government regulations, pharmaceutical and fine chemical manufacturers are increasingly seeking to replace stoichiometric reagents used in synthetic transformations with catalytic routes in order to develop greener, safer, and more cost-effective chemical processes.

This book supports the discovery, development, and implementation of new catalytic methodologies on a process scale, opening the door to the sustainable production of pharmaceuticals and fine chemicals.Pairing contributions from leading academic and industrial researchers, Sustainable Catalysis focuses on key areas that are particularly important for the fine chemical and pharmaceutical industries, including chemo-, bio-, and organo-catalytic approaches to C-H, C-N, and C-C bond-forming reactions.

Chapters include academic overviews of current innovations and industrial case studies at the process scale, providing new insights into green catalytic methodologies from proof-of-concept to their applications in the synthesis of target organic molecules.Sustainable Catalysis provides the foundation needed to develop sustainable green synthetic procedures, with coverage of such emerging topics as: Catalytic reduction of amides avoiding LiAlH4 or B2H6Synthesis of chiral amines using transaminasesIndustrial applications of boric acid and boronic acid catalyzed direct amidation reactionsC-H activation of heteroaromaticsOrganocatalysis for asymmetric synthesisOffering a balanced perspective on current limitations, challenges, and solutions, Sustainable Catalysis is recommended for synthetic organic chemists seeking to develop new methodologies and for industrial chemists dedicated to large-scale process development.



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